Diabetes causes numerous complications. Among these include poor sensation and decreased microcirculation in the feet, which can ultimately lead to pressure sores. Diabetes also affects the body's ability to heal wounds and fight off bacteria. When these two complications are combined, that puts diabetics at a greater risk for developing pressure sores that do not heal and become infected. When the infection is not promptly treated, or is bad enough, it can spread to the bone or even up the leg. If this cannot be cured by other measures, then an amputation must be performed of the infected part to preserve the health of the rest of the leg or the body itself.